Final grade weighting is the way all of your assignments from the Coursework page are combined to determine each student's final grade. In many cases, you will already have this spelled out in your syllabus -- now you simply need to bring those details into the Gradebook portlet.
Setting up your final grade weighting is a two-step process.
First, you need to select (or create) a grade weighting method, which determines the grouping and parameters that will be used in calculating the final grade. You can do that on the Weighting Method screen.
After you have a weighting method set up, you need to input the actual weighting values (if necessary -- some methods, like "Point" and "Unit," handle weighting fully automatically!). You input these weighting values on this screen in the table below, and (depending on your method) by clicking a unit or type to weight assignments within. If your method does any automatic weighting, you can see the current weight values of all of your items on this screen as well.