It is important to do an audience analysis to know your audience. It is important to keep your audience attention. One way of doing this is to find out what is important to them and try to focus on those subjects. For example: When I have to address different groups in my profession I had to learn early in my career that you can lose an audience real fast speaking upon anything that does not directly affect them. I once addressed a group of people who kids were in sports but I used examples dealing band. I learned that day had I used examples dealing with groups or teams I would have had more of their attention.
Thanks for bringing sex, age, and orientation to the forefront. I fail to mention those in my response because it simply didn't cross my mind. These are probably three of the most important things to know about your audience.
Romell I can only imagine speaking on a topic without the proper research only to find out I am offending everyone in the audience. That would be disastrous to say the least. I try to feed of the audience and give them more of what they want. Great example about the video games.